The gold-standard GLP-1 — proven for years, priced for real people.
Compounded semaglutide is the same active ingredient as Ozempic® and Wegovy® — prescribed by licensed physicians, shipped to your door in 2–3 days. Starting at $199/mo. No insurance. No pharmacy lines.
What is compounded semaglutide?
Semaglutide is the active ingredient in Ozempic® and Wegovy® — two of the most widely prescribed and extensively studied weight loss medications in the world. Compounded semaglutide contains the same active ingredient, prepared by a licensed 503B compounding pharmacy under FDA oversight, at a fraction of the brand-name cost.
Semaglutide works by mimicking GLP-1, a natural hormone your body produces after eating. It signals your brain that you're full, slows digestion, and reduces the constant hunger that makes dieting feel impossible. Over time, your appetite recalibrates — and weight loss becomes something that happens naturally, not something you have to white-knuckle your way through.
At VYVA Health, a licensed physician reviews your intake, prescribes the right starting dose for your body, and monitors your progress every step of the way. No insurance required. No prior authorization battles. Just a straightforward path to real, lasting results.
How semaglutide works in your body
One hormone. One weekly injection. A completely different relationship with food.
Mimics your natural GLP-1 hormone
GLP-1 is released naturally after you eat — it tells your brain you're satisfied. Semaglutide keeps that signal active far longer than your body normally would, so you feel full faster and stay full longer.
Slows gastric emptying
Food moves through your stomach more slowly, reducing post-meal blood sugar spikes and extending the feeling of fullness. Cravings between meals fade. Portion sizes shrink naturally — without willpower.
Resets your hunger baseline over time
After weeks of treatment, your body recalibrates its hunger signals. The constant background noise of food cravings quiets down. Most patients describe it as finally feeling in control of their eating for the first time.
What results can you expect?
Based on the STEP clinical trial program — the largest semaglutide weight loss study ever conducted, with over 4,500 participants.
Appetite begins to shift
Most patients notice reduced hunger and smaller natural portion sizes within the first 2–4 weeks. Some experience mild nausea as the body adjusts — this typically fades within 1–2 weeks.
Visible, measurable weight loss
Average loss of 4–6% body weight in the first 3 months. Clothes fit differently. Energy improves. Blood sugar and blood pressure often begin to normalize without additional medication.
Momentum builds
Weight loss continues to compound as the dose is gradually increased. Most patients are 8–12% below their starting weight. The new eating patterns start to feel natural, not forced.
Up to 15% body weight lost
At the maintenance dose in clinical trials, participants lost an average of 15% of their body weight — more than any other single-pathway GLP-1 studied before tirzepatide. Many patients continue losing beyond 12 months.
Compounded semaglutide vs. brand-name alternatives
Same active ingredient as Ozempic® and Wegovy®. A fraction of the price.
Who is a good candidate for semaglutide?
Semaglutide is typically prescribed for adults who meet one or more of the following criteria.
- BMI of 30 or higher (obesity)
- BMI of 27 or higher with a weight-related condition (type 2 diabetes, high blood pressure, high cholesterol, or sleep apnea)
- Have tried diet and exercise without achieving lasting results
- Are not pregnant or planning to become pregnant
- Do not have a personal or family history of medullary thyroid carcinoma (MTC) or MEN 2 syndrome
- Do not have a history of pancreatitis or severe gastrointestinal disease
Not sure if you qualify? Complete our free intake form and a licensed physician will review your health profile and respond within 24 hours.
Side effects — what to expect
Most side effects are mild and temporary, occurring most often when starting treatment or when your dose is increased. They typically resolve within 1–2 weeks as your body adjusts.
- NauseaThe most commonly reported side effect, especially in the first few weeks. Usually mild and fades quickly.
- Reduced appetiteExpected and intentional — this is the medication doing exactly what it's supposed to.
- FatigueSome patients feel tired in the first 1–2 weeks as the body adjusts to the new hormone signal.
- Constipation or diarrheaGI changes are common early in treatment. Staying well-hydrated and eating fiber-rich foods helps.
- Injection site reactionsMild redness or irritation at the injection site. Rotating sites weekly minimizes this.
This is not a complete list of side effects. Your VYVA Health physician will review your full medical history and discuss all risks and benefits before prescribing.
Semaglutide vs. tirzepatide — which is right for you?
Both are powerful, proven GLP-1 medications. Here's how to think about the choice.
Choose semaglutide if…
- You want the most clinically established option with 5+ years of real-world data
- You're looking for the most affordable starting price ($199/mo)
- You prefer a well-understood side effect profile
- Your physician recommends a single-pathway GLP-1 for your health profile
Consider tirzepatide if…
- You want the maximum possible weight loss (up to 22.5% vs. 15%)
- You have type 2 diabetes or insulin resistance alongside obesity
- You've tried semaglutide and want to explore a dual-action option
- Your physician recommends a dual GIP + GLP-1 approach
Not sure which to choose? Our physicians review your full health profile and recommend the best fit for your body and goals.
Frequently asked questions
Ready to stop fighting your body — and start working with it?
Complete your free intake form in under 5 minutes. A licensed physician reviews your profile and responds within 24 hours.